Download PDF by Paul C. Guest: Biomarkers and Mental Illness: It’s Not All in the Mind

By Paul C. Guest

ISBN-10: 3319460870

ISBN-13: 9783319460871

ISBN-10: 3319460889

ISBN-13: 9783319460888

Employing available language all through, this e-book covers the historical past of psychiatric study, the present state-of-the artwork in psychiatric perform, the physiological structures laid low with psychiatric health problems, the whole-body nature of those illnesses and the effect that this point has on rising biomarker discoveries.

Further, it presents descriptions of the main particular psychiatric issues and the specified demanding situations concerning the analysis and therapy of every. The booklet concludes with insights into the most recent advancements in handheld biomarker try out units, which could offer diagnostic details in under quarter-hour in point-of-care settings.

This booklet investigates the rising use of biomarkers within the learn of psychiatric ailments, a subject matter of substantial significance for a large variety of individuals together with researchers, clinicians, psychiatrists, college scholars or even these whose lives are affected not directly by way of a psychiatric ailment. The final class is hardly ever trivial, considering the fact that a marvelous one in 3 humans world wide exhibit the factors for no less than one psychiatric illness sooner or later of their lifetime.

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Thus, patients could be divided into subgroups of likely responders and non-responders and at risk or not at risk of developing side effects, respectively. The evidence would be used for making decisions on the medications that patients should receive. Examples of biomarkers which could be used for this could include those derived from imaging techniques, serum assays, genetic profiling, physiological measures, histopathological findings or psychological tests. There are already some examples of genomic biomarker tests that predict response of patients receiving a drug based on how quickly that drug is metabolized within the patients’ bodies.

However, new biomarker profiling platforms have emerged which allow the simultaneous measurement of hundreds or even thousands of molecules. This has helped to increase accuracy of the findings, reduce the amount of sample required and lower the overall costs in comparison to techniques which measure one biomarker at a time. Furthermore, recent efforts have seen movements towards miniaturization of biomarker assays on handheld devices which can produce results during the time of a standard visit to the doctor’s office.

Based on this, she was prescribed treatment with olanzapine. However, the hallucinations were still present after 1 week and delusions also began to emerge. One of these was the belief that her parents were poisoning her food. She was therefore admitted to a psychiatric hospital, where several clinical diagnoses were considered. These included psychotic disorder nototherwise-specified, schizophreniform disorder, major depressive disorder and psychotic/mood phenomena with a personality disorder. Routine neurological examinations and laboratory tests were performed but these showed no abnormalities.

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Biomarkers and Mental Illness: It’s Not All in the Mind by Paul C. Guest


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