Cellular and Molecular Biology of Metals by Rudolfs K. Zalups, D. James Koropatnick PDF

By Rudolfs K. Zalups, D. James Koropatnick

ISBN-10: 1420059971

ISBN-13: 9781420059977

With bankruptcy contributions from greater than 30 steel biology specialists, mobile and Molecular Biology of Metals explains the position of key divalent steel ions eager about the molecular and mobile biology of assorted aim mobilephone populations. even though it essentially specializes in homeostatic metals, equivalent to nickel, zinc, and chromium, the textual content additionally discusses a number of environmentally pertinent, poisonous divalent cations, together with mercury, cadmium, and arsenic. This authoritative source reports the physiological mechanisms underlying the dealing with of crucial and poisonous steel ions, together with steel ion homeostasis, metals and enzyme task, metals and transcriptional rules, and steel ion delivery. It additionally analyzes different capabilities designed to prevent metal-induced toxicity and mediate the steel enhancement of mobile functionality. The position of steel ions and their influence on mammalian cells and organs are just commencing to be really outlined. mobile and Molecular Biology of Metals fingers metals toxicologists and mobile and molecular biologists with the required wisdom they should take the study attempt to the following point.

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Download e-book for kindle: Cellular and Molecular Biology of Metals by Rudolfs K. Zalups, D. James Koropatnick

With bankruptcy contributions from greater than 30 steel biology specialists, mobile and Molecular Biology of Metals explains the function of key divalent steel ions considering the molecular and mobile biology of varied aim cellphone populations. even though it essentially makes a speciality of homeostatic metals, resembling nickel, zinc, and chromium, the textual content additionally discusses a couple of environmentally pertinent, poisonous divalent cations, together with mercury, cadmium, and arsenic.

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42. , Developmental consequences of trace mineral deficiencies in rodents: Acute and long-term effects, J. , 133(5 Suppl 1), 1477S, 2003. 43. , Biological function of metallothionein. V. Its induction in rats by various stresses, Am. J. , 234, E282, 1978. 44. , A startling role for synaptic zinc, Neuron, 52, 572, 2006. © 2010 by Taylor and Francis Group, LLC 28 Cellular and Molecular Biology of Metals 45. , Zinc, antioxidant systems and metallothionein in metal-mediated apoptosis: Biochemical and cytochemical aspects, Comp.

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Chem. , 129, 10911, 2007. 55. , Folding pathway of apometallothionein induced by Zn2+, Cd2+ and Co2+, J. Inorg. , 88, 144, 2002. 56. J. , Keep your fingers off my DNA: Protein–protein interactions mediated by C2H2 zinc finger domains, Cell. Biochem. , 50, 111, 2008. 57. , Structures of zinc finger domains from transcription factor Sp1. Insights into sequence-specific protein–DNA recognition, J. Biol. , 272, 7801, 1997. 58. , Metabolism of cadmium, zinc and copper in the rat kidney: The role of metallothionein and other binding sites, Environ.

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Cellular and Molecular Biology of Metals by Rudolfs K. Zalups, D. James Koropatnick


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