New PDF release: Cholesterol: Its Functions and Metabolism in Biology and

By Simon M. Jackson, Johan Ericsson, Peter A. Edwards (auth.), Robert Bittman (eds.)

ISBN-10: 1461377072

ISBN-13: 9781461377078

ISBN-10: 1461559014

ISBN-13: 9781461559016

Experts examine the biochemical and biomedical facets of ldl cholesterol, addressing its metabolism in basic and affliction states. They speak about a extensive diversity of themes, together with key steps within the ldl cholesterol biosynthetic pathway, and the position of ldl cholesterol in melanoma, atherosclerosis, and illnesses of the worried procedure. The book's finished assurance additionally contains the pathological effects and strength remedies for varied affliction states, and the improvement of latest anti-atherogenic drugs.

Show description

Read or Download Cholesterol: Its Functions and Metabolism in Biology and Medicine PDF

Similar biology books

Apoptosis Methods and Protocols - download pdf or read online

A suite of state of the art ideas for detecting and quantifying apoptosis, figuring out its biochemistry, and for choosing the genes and proteins that control and hold it out. defined in step by step element, those comfortably reproducible tools diversity from circulate cytometry and immunohistochemical strategies to kinase job assays, yeast two-hybrid screening, and the cloning of novel genes by means of differential expression.

Download PDF by Rudolfs K. Zalups, D. James Koropatnick: Cellular and Molecular Biology of Metals

With bankruptcy contributions from greater than 30 steel biology specialists, mobile and Molecular Biology of Metals explains the function of key divalent steel ions fascinated with the molecular and mobile biology of assorted aim telephone populations. even though it basically specializes in homeostatic metals, resembling nickel, zinc, and chromium, the textual content additionally discusses a couple of environmentally pertinent, poisonous divalent cations, together with mercury, cadmium, and arsenic.

New PDF release: The Cytoskeleton: An Introductory Survey

The time period cytoskeleton has turn into firmly validated in ultra-modern clinical vocabulary. certainly, it's tough to think that purely ten years in the past, it was once nearly non-existent. for the reason that then, the trendy box of analysis at the structural association of the cytoplasm has changed into the most effective and swiftly increasing examine parts in mobile Biology this present day.

Extra info for Cholesterol: Its Functions and Metabolism in Biology and Medicine

Example text

1995). It is not known whether these latter changes are directly related to apoptosis. Inhibition of HMG-CoA reductase by mevinolin is also reported to result in apoptosis (Perez-Sala and Mollinedo, 1994), even though such treatment inhibits the biosynthesis of famesyl diphosphate, and, presumably, famesol. Thus, the physiological relationship between apoptosis and intracellular isoprenoid alcohol levels remains to be clearly established. 6. ISOPRENOIDS AS TRANSCRIPTIONAL REGULATORS Ecdysone is an insect steroid hormone that controls important regulatory events leading to moulting and metamorphosis.

10. REFERENCES Alberts, A. , 1980, A highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent, Proc. Nati. Acad. Sci. USA 77:3957-3961. Anderson, R. G. , 1993, Caveolae: Where incoming and outgoing messengers meet, Proc. Natl. Acad. Sci. USA 90:10904-10913. , 1995, Retinoid agonist activities of synthetic geranyl geranoic acid derivatives, Biochem. Biophys. Res. Commun. 209:66-72. , 1995, Low density lipoprotein (LDL) cholesterol is converted to 27hydroxycholesterol in human fibroblasts, 1.

1988, Multivalent control of 3-hydroxy-3methylglutaryl coenzyme A reductase. Mevalonate-derived product inhibits translation of mRNA and accelerates degradation of enzyme, 1. Bioi. Chem. 263:8929-8937. Nicholson, D. , Thornberry, N. , Vaillancourt, J. , Ding, C. , Griffin, P. , Lazebnik, Y. , Munday, N. , Raju, S. , Smulson, M. , Yu, V. , and Miller, D. , 1995, Identification and inhibition of the ICEICED-3 protease necessary for mammalian apoptosis, Nature 376:37-43. , 1990, Rat liver cholesterol 7a-hydroxylase: Pretranslational regulation for circadian rhythm, 1.

Download PDF sample

Cholesterol: Its Functions and Metabolism in Biology and Medicine by Simon M. Jackson, Johan Ericsson, Peter A. Edwards (auth.), Robert Bittman (eds.)

by Paul

Rated 4.45 of 5 – based on 30 votes
This entry was posted in Biology.