By Simon M. Jackson, Johan Ericsson, Peter A. Edwards (auth.), Robert Bittman (eds.)
Experts examine the biochemical and biomedical facets of ldl cholesterol, addressing its metabolism in basic and affliction states. They speak about a extensive diversity of themes, together with key steps within the ldl cholesterol biosynthetic pathway, and the position of ldl cholesterol in melanoma, atherosclerosis, and illnesses of the worried procedure. The book's finished assurance additionally contains the pathological effects and strength remedies for varied affliction states, and the improvement of latest anti-atherogenic drugs.
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Extra info for Cholesterol: Its Functions and Metabolism in Biology and Medicine
1995). It is not known whether these latter changes are directly related to apoptosis. Inhibition of HMG-CoA reductase by mevinolin is also reported to result in apoptosis (Perez-Sala and Mollinedo, 1994), even though such treatment inhibits the biosynthesis of famesyl diphosphate, and, presumably, famesol. Thus, the physiological relationship between apoptosis and intracellular isoprenoid alcohol levels remains to be clearly established. 6. ISOPRENOIDS AS TRANSCRIPTIONAL REGULATORS Ecdysone is an insect steroid hormone that controls important regulatory events leading to moulting and metamorphosis.
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Cholesterol: Its Functions and Metabolism in Biology and Medicine by Simon M. Jackson, Johan Ericsson, Peter A. Edwards (auth.), Robert Bittman (eds.)