By H. P. Schwan (auth.), Eberhard Neumann, Arthur E. Sowers, Carol A. Jordan (eds.)
Cells might be humorous. attempt to develop them with a marginally improper recipe, they usually flip over and die. yet hit them with an electrical box robust sufficient to knock over a horse, and so they do sufficient issues to justify overseas conferences, to fill a large booklet, and to steer one to talk of a wholly new expertise for mobile manipulation. The very improbability of those occasions not just increases questions on why issues take place but additionally ends up in a protracted record of sensible structures during which the applying of robust electrical fields may perhaps permit the merger of telephone contents or the creation of alien yet very important fabric. necessarily, the elemental questions and the sensible purposes won't retain in step. The questions are intrinsically difficult. it really is demanding adequate to investigate the motion of the fairly susceptible fields that rotate or align cells, however it is sort of most unlikely to foretell responses to the cell-shredding bursts of electrical energy that make them fuse or to divulge heart's contents to very huge molecular assemblies. on the other hand, theoretical stories and systematic exam of version structures have produced a few creditable effects, principles which may still finally supply tricks of what to aim next.
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Additional resources for Electroporation and Electrofusion in Cell Biology
The expected resonance at 30 MHz and an unexpected and yet unexplained second one around 80 MHz were observed. As for AC fields, theory predicts a linear dependence of the spinning rate on the square of the field strength. This was indeed observed in all frequency ranges, with all cells and under all chosen conditions. In the steady state when the Stokes force of friction equals the torque on the cell, the spinning rate should be inversely proportional to the viscosity of the surrounding liquid.
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9:399-409. Cellular Spin Resonance 35 Pohl, H. , 1983a, Cellular spinning in pulsed rotating electric fields, J. Bioi. Phys. 11:59-62. Pohl, H. , 1983b, The spinning of suspended particles in a two-pulsed, three-electrode system, J. Bioi. Phys. 11:66-68. Pohl, H. , 1982, Cellular spin resonance of aging yeast and mouse sarcoma cells, J. Bioi. Phys. 10:17-30. Pohl, H. , and Crane, J. , 1971, Dielectrophoresis of cells, Biophys. J. 11:711-727. , 1896, Dber Rotationen im constanten electrischen Felde, Ann.
Electroporation and Electrofusion in Cell Biology by H. P. Schwan (auth.), Eberhard Neumann, Arthur E. Sowers, Carol A. Jordan (eds.)