By G. W. Richter
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Extra info for International Review of Experimental Pathology. Kidney Disease
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78, 108. , and McGuckin, J. (1972). Prostaglandins 2, 393. Piperno, E. (1981). In "Toxicology of the Kidney" (J. B. ), pp. 31-35. Raven, New York. Plotz, P. H. and Kimberley, R. P. (1981). Arch. Intern. Med. 141, 343. Powell, C. , Bach, P. , and Bridges, J. W. (1983). Hum. Toxicol. 2, 565. Powell, C. , Bach, P. , and Bridges, J. W. (1985a). In "Renal Heterogeneity and Target Cell Toxicity" (P. H. Bach and E. A. ), pp. 195-198. Wiley, Chichester. Powell, C. , Hall, D. , Bach, P. , and Bridges, J.
9. Apex-limited urothelial hyperplasia following five daily doses of 5 mmol/kg N-PAA. Hematoxylin-eosin, x 5 . ] ^ f* B RPN AND UPPER UROTHELIAL CARCINOMA 37 the extent of the lesion caused by these agents (Rosner, 1976; Bach and Bridges, 1984; Bach and Hardy, 1984), have so far precluded the experi mental investigation of the relationship between RPN and upper urothelial carcinoma. The acute nature of the BEA-induced RPN, without extrarenai toxicity and with limited effects on the renal cortex, offers a less compli cated model to study pelvic urothelial changes and the factors that may exacerbate the process.
International Review of Experimental Pathology. Kidney Disease by G. W. Richter