By John Jay Halperin
Offering the scientific practitioner with a extensive clinical realizing, this ebook discusses the causative organism, its needful atmosphere, sickness epidemiology, host-Borrelia interactions, diagnostic trying out, scientific manifestations, healing innovations, and long-term analysis. It explicitly stories either the elemental biology of the an infection and sensible medical features, linking the 2 to illustrate what's and isn't caused by this an infection. it really is an authoritative advisor for medics and researchers concerned with diagnosing and treating Lyme, masking biology, epidemiology and therapeutics.
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Additional resources for Lyme Disease: An Evidence-Based Approach (Advances in Molecular and Cellular Biology Series)
To this day, T. pallidum cannot be cultured in vitro. , 1916). The basis of his method included the use of rabbit kidney as the major source of nutrients, human ascitic fluid free of bile and a thickening agent such as gelatin (Noguchi, 1912b). 33 In 1922, Kligler and Robertson improved Noguchi’s medium for the culture of louseborne B. recurrentis by defining conditions to maintain and grow the spirochaete consistently (Kligler and Robertson, 1922). The major problem with Noguchi’s medium was its inconsistent results.
Fish, D. A. (2009) Climate and seasonality are predictors of Borrelia burgdorferi genotype distribution. Applied and Environmental Microbiology 75, 2476–2483. , Kurtenbach, K. and Fish, D. (2009) Phylogeography of Borrelia burgdorferi in the eastern United States reflects multiple independent Lyme disease emergence events. Proceedings of the National Academy of Sciences USA 106, 15013–15018. Gern, L. -F. (2002) Ecology of Borrelia burgdorferi sensu lato in Europe. S. and Stanek, G. (eds) Lyme Borreliosis.
Bissettii No North America Bissett and Hill (1987); Postic et al. (1998) Europe Strle et al. (1997) Asia Masuzawa et al. (2001) B. sinica No B. turcica No Asia Guner et al. (2004) B. spielmanii B. carolinensis B. californiensis Yes No No Europe North America North America van Dam et al. (1993); Richter et al. (2004) Rudenko et al. (2010) Postic et al. (2007) B. bavariensis No Europe Margos et al. (2009) B. yangtze No Asia Chu et al. (2008) a Only species regularly isolated from patients with Lyme disease are considered to be pathogenic.
Lyme Disease: An Evidence-Based Approach (Advances in Molecular and Cellular Biology Series) by John Jay Halperin