Download e-book for iPad: Mechanical Engineering of the Cytoskeleton in Developmental by Richard Gordon (Eds.)

By Richard Gordon (Eds.)

ISBN-10: 0123645530

ISBN-13: 9780123645531

Constructing organisms are structures during which the geometry, dynamics, and boundary stipulations are all altering during morphogenesis. The morphogenesis of cells and organisms seem to be mediated partially by means of the robotically energetic parts of the cytoskeleton. Mechanical forces have lengthy been thought of secondary to the results of molecular mechanisms in phone progress, differentiation, and improvement. This quantity explores the position of mechanical forces in mobilephone progress and improvement and demonstrates its significance. This quantity will end up necessary to all biologists drawn to the basics of mechanical forces in improvement, from the complex to the graduate researcher.

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Extra resources for Mechanical Engineering of the Cytoskeleton in Developmental Biology

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X. Some Views on a Mechanical Approach t o Ontogenetic Processes Mechanical stresses, in their simplest form being osmotically driven, should be considered as one of the most universal and phylogenetically ancient physical properties of living cells, including the Prokaryota (Harold, 1990). , Allan and Harrison, 1980; Ben Ze’ev, 1985; Braam and Davis, 1990). The idea has also been put forward that mechanically mediated cytoskeleta1 mechanisms may play a crucial role in developmental phenomena related traditionally to chemical inducers (Gordon and Brodland, 1987).

The protrusion-generating regime typical for the stretched suprablastoporal cells (arrows) is abruptly shifted to the microvilligenerating regime in the invaginating blastoporal cells (F, pointer). In E, the protrusive regime of a suprablastoporal cell is combined with the production of a few microvilli by the same cell. In B, E, and F, the outer cell membranes are stained with Ruthenium red. Bar = I gm. , 1988). 21 22 L. V. BELOUSSOV €7 AL. to-volume ratio (Fig. 8E-G). On the other hand, as shown earlier, tissue stretching promotes cell intercalation (Fig.

Bretcher, M. S. (1988). Fibroblasts on the move. J. Cell Biol. 106, 235-237. Burnside, B . (1971). Microtubules and microfilaments in newt neurulation. Deu. Biol. 26, 416-441. Christensen, 0. (1987). Mediation of cell volume regulation by Ca influx through stretchactivated channels. Nature (London) 330, 66-68. Dennerly, T. , Buxbaum, R. , and Heidemann, S. R. (1989). The cytomechanics of axonal elongation and retraction. J . Cell B i d . 109, 3073-3083. , and Wohlfarth-Bottermann, K. E. (1975).

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Mechanical Engineering of the Cytoskeleton in Developmental Biology by Richard Gordon (Eds.)

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