By Massimo Pietropaolo, George S. Eisenbarth (auth.), Boris Draznin MD, PhD, Derek LeRoith MD, PhD (eds.)
In a swiftly evolving and intensely very important zone of clinical technological know-how, it's always tough for the coed, instructor, and researcher to maintain abreast of all of the very important advances. the aim of Molecular Biology ofDiabetes, elements I and II is to convey to those members the most recent wisdom of diabetes-related learn in a accomplished, but concise demeanour. To this finish, we've got assembled chapters, written through many of the world's specialists within the box, that we think compre hensively survey and synthesize a coherent figuring out of the topic. reviews of the etiology of style I and sort II diabetes are tremendous fascinating and crucial, for the reason that we are hoping to 1 day hinder the illness utilizing gene treatment. those points are coated in Molecular Biology of Diabetes: I. Autoimmunity and Genetics; Insulin Synthesis and Secretion. In style II diabetes, an abnormality in pancreatic secretion exists concomitantly with peripheral insulin resistance. This abnor mality of insulin secretion is assumed to be with regards to a defect(s) in glucose sensing. Uncoupling of glucose sensing from insulin secre tion could be the the most important step within the pathogenesis of noninsulin-depen dent diabetes. during this quantity, we've got invited authors to explain their reviews on all identified components affecting ~-cell functionality, together with autoimmunity and genetics of diabetes, in addition to molecular mecha nisms of insulin synthesis and secretion. within the previous few years, the main quickly advancing sector of analysis in diabetes has been, in truth, on the topic of insulin action.
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Additional resources for Molecular Biology of Diabetes: I. Autoimmunity and Genetics; Insulin Synthesis and Secretion
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Molecular Biology of Diabetes: I. Autoimmunity and Genetics; Insulin Synthesis and Secretion by Massimo Pietropaolo, George S. Eisenbarth (auth.), Boris Draznin MD, PhD, Derek LeRoith MD, PhD (eds.)